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KMID : 0377619740260010063
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Korean Jungang Medical Journal
1974 Volume.26 No. 1 p.63 ~ p.67
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A Comparison of Serum-HSAP and Urinary Estrogen excretion in Pregnancy as a Placental Function test
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Abstract
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The serum heat stable alkaline phosphatase (S-HSAP) was assayed to measure only the placental iso-enzymes in a group of normal pregnant women in order to establish the normal range. Ninety four paired estimations of serum heat stable alkaline phosphatase and urinary estrogen excretion were performed on normal or patients with complication of pregnancy. Serum-HSAP determinations were found to be of no use in predicting fetal -distress of fetal dysmaturity.
Serial assays of urinary estrogen output enabled dysmaturity to be correctly predicted in 63.7 percent of cases, but there was also an incidence of 18.2 percent false positive predictions.
There was no correlation between the serum HSAP and fetal weight, and urinary estrogen output and placental weight, although there are correlations between the serum HSAP and placental weight or urinary estrogen output and fetal weights.
Urinary estrogen assays were less reliable in predicting fetal distress and Serum HSAP levels are probably of no value in the prediction of a small-for-dates baby.
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